2 words: commercial software
This thread is hilarious. I'm no computer guru like you guys and yet I can think of piles of essential (non-substitutable) software that runs ONLY on Windows & Mac.
Much of this list runs better on a Windows OS, some of it runs Only on a 64-bit Windows OS. Some of it
may run on Linux (I'm guessing that mental ray does)... and some of it when run on Linux will be broken in various ways... which I'd venture to say means that it doesn't run under Linux by definition, unless diminished and missing key functionality somehow counts as a "feature".
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Vue
Mac OS X v10.5+ 32/64,
Windows XP/Vista/Windows 7 32/64
Adobe products:
Windows & MAC: W
in XP & 7; Win 7 SP1(64 bit) req. for Premiere Pro, After Effects & Encore; Win 7 sp1 req. for SpeedGrade
Mac OS X v10.6.8 or v10.7 - Adobe Creative Suite 5, 5.5, and CS6 support Mac OS X Mountain Lion (v10.8) when installed on Intel based systems. Refer to the CS6 FAQ for more information about Mac OS X Mountain Lion support.**
Photoshop Extended
Photoshop® CS6 Extended
Illustrator
Illustrator® CS6
InDesign
InDesign® CS6
Acrobat Pro
Acrobat® X Pro
Flash Professional
Flash® Professional CS6
Flash Builder
Flash Builder® 4.6 Premium Edition
Dreamweaver
Dreamweaver® CS6
Fireworks
Fireworks® CS6
Adobe Premiere Pro
Adobe Premiere® Pro CS6
After Effects
After Effects® CS6
Adobe Audition
Adobe Audition® CS6
SpeedGrade
SpeedGrade CS6
Adobe Prelude
Prelude CS6
Encore
Encore® CS6
Bridge
Bridge CS6
Media Encoder
Media Encoder CS6
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Autodesk Products: Windows & Mac only
some can be run under linux with loss of key functionality
which means that they don't work. Example from the autodesk website:
"Note: Maya 2013 is also capable of running on other configurations such as boutique distributions of Linux. However, enumerating systems that are not tested and cannot be supported or that fall below the requirements for a productive user experience is beyond the scope of the online certification charts."
AutoCAD
AutoCAD for Mac
AutoCAD Architecture
AutoCAD Civil 3D
AutoCAD Design Suite
AutoCAD Electrical
AutoCAD Freestyle
AutoCAD Inventor LT Suite
AutoCAD LT
AutoCAD LT for Mac
AutoCAD Map 3D
AutoCAD Mechanical
AutoCAD MEP
AutoCAD OEM
AutoCAD P&ID
AutoCAD Plant 3D
AutoCAD Raster Design
AutoCAD Revit Architecture Suite
AutoCAD Revit MEP Suite
AutoCAD Revit Structure Suite
AutoCAD Structural Detailing
AutoCAD Utility Design
AutoCAD WS
Autodesk 123D
Autodesk 123D Sculpt
Autodesk 360 Mobile App
Autodesk 3ds Max
Autodesk 3ds Max Design
Autodesk 3ds Max Entertainment Creation Suite
Autodesk Alias Products
Autodesk Alias Design
Autodesk Alias Surface
Autodesk Alias Automotive
Autodesk Beast
Autodesk BIM 360
Autodesk Building Design Suite
Autodesk Buzzsaw
Autodesk Constructware
Autodesk Design Review
Autodesk DWF Writer
Autodesk Ecotect Analysis
Autodesk Entertainment Creation Suites
Autodesk Fabrication CADmep
Autodesk Fabrication CAMduct
Autodesk Fabrication ESTmep
Autodesk Fabrication FABmep
Autodesk Factory Design Suites
Autodesk FBX
Autodesk Flame
Autodesk Flame Premium
Autodesk Flare
Autodesk Fluid FX
Autodesk ForceEffect
Autodesk ForceEffect Motion
Autodesk Freewheel
Autodesk GIS Design Server
Autodesk Green Building Studio
Autodesk HumanIK
Autodesk Homestyler
Autodesk Impression
Autodesk Infrastructure Design Suite
Autodesk Infrastructure Map Server
Autodesk Infrastructure Modeler
Autodesk Inventor Engineer-to-Order
Autodesk Inventor Products
Autodesk Inventor Fusion
Autodesk Inventor Publisher
Autodesk Inventor LT
Autodesk Kynapse
Autodesk Lustre
Autodesk Maya
Autodesk Maya Entertainment Creation Suite
Autodesk MotionBuilder
Autodesk Mudbox
Autodesk Navisworks Products
Autodesk Navisworks Manage
Autodesk Navisworks Simulate
Autodesk Navisworks Review
Autodesk Navisworks Freedom
Autodesk Plant Design Suite
Autodesk PLM 360
Autodesk Product Design Suite
Autodesk Opticore Studio Professional
Autodesk Quantity Takeoff
Autodesk Revit
Autodesk Revit Architecture
Autodesk Revit LT
Autodesk Revit MEP
Autodesk Revit Structure
Autodesk Robot Structural Analysis Professional
Autodesk Scaleform
Autodesk Seek
Autodesk Showcase
Autodesk Simulation 360
Autodesk Simulation CFD
Autodesk Simulation DFM
Autodesk Simulation Mechanical and Multiphysics
Autodesk Simulation Moldflow
Autodesk SketchBook Designer
Autodesk SketchBook Pro
Autodesk Smoke
Autodesk Softimage
Autodesk Stitcher Unlimited
Autodesk Streamline
Autodesk Time FX
Autodesk TinkerBox
Autodesk Vault Products
Autodesk Vault Collaboration
Autodesk Vault Collaboration AEC
Autodesk Vault Professional
Autodesk Vault Workgroup
AutoSketch
CAiCE Visual Transportation Products
DWG TrueView
DWG TrueConvert
mental ray
Motion FX
ObjectARX
Pixlr