I prefer UNO to Crazy 8's but will play either. Anything else and I get bored too quickly.
Thanks for reminding me, I need to reinstall my Hoyle Card Games.
Just for reference: The 2003 version is one of the best. If you can find it thats the one to get. The last few years have really stunk, especially 2009.
EDIT:
I guess I should come clean. I played Magic back in Jr High. I had mostly Alphas and Betas and some Revised. By the time 4th edition came out I was tired of it. Too damn expensive. WotC got insanely greedy and took all the joy out of the game.
I did get the Microprose PC game when it came out. Pretty darn good while I played it on Win98, but it doesnt work well under Windows XP. There are some special instructions on the internet for getting it to work but its so damn painful its not worth it.