Originally posted by: piasabird
22-250 is a very high velocity round. That is because it has a lower caliber round and the amount of charge is very high for the weight of the bullet.
It may be illegal in most places but I have seen a few .50 caliber snyper type rifles. They make some of the rounds with teflon coatings. When I worked at Winchester Western we use to special order the bullets and we made them for the military. They would be considered armored piercing. These rifles that shoot this round are quite large usually uses a tripod and the range is about 2 miles. I am guessing at the range. It is ideal for an offensive weapon or for a sniper.
If you have the civilian version of the 7.62 or militray rifle M-16(guess), I have seen people hit targets at 1,000 meters or more at the rifle range. The shell cases for the military were heat treaded to make them harder. I am guessing that the gun powder that was used in these rounds was quite powerful. I was in the army and this round is leathal at short range. They can easily pierce both sides of an empty ammo can and the round expands on impact for a good killing effect. I have served in the military and I also worked on these size of shell casings at Olin Works of East Alton, Winchester Western.
Some of the larger rounds may not travel quite as far due to their weight. The larger grain size of the bullets is more for taking down larger game. The 300 Winmags are extremely large shell cases. I use to hate trying to keep that hopper full of shell cases for this size cartridge. The 270 is a typical hunting round and very popular. The 30.30 is barely tapered and does not have a reduced neck. It is a popular round but it is more of a varmit round for ranchers.
Here is an article about hunting rifle accuracy:
http://www.rifleshootermag.com/shooting_tips/accuracy_1001/
There must be a hundred hunting shows and magazines you could find online.
A larger caliber may have such a recoil that you dont want to shoot twice. For instance when hunting Bear you dont want to be too close or have a light round.