Both chipsets are good, and mature. That said, I would give the nod to the nForce3 250Gb chipset. It is faster (although this can be motherboard dependent as well), and uses less CPU cycles for USB, SATA, PATA, etc. The most stable motherboard boasting the nForce3 250Gb chipset also happens to be one of the least expensive--the Soltek K8AN2E-GR, which can be found for a paltry $85 at NewEgg. Another item in favor of the nForce3 250Gb chipset is the native gigabit ethernet. This is something that the VIA chipset does not possess. The Soltek board does not overclock well, but it is one of the fastest and definitely hell-on-wheels stable at stock speed. Highly recommended.