Technically I voted Yes, but I probably should of voted no, heres why:
I use a trackball, but only a very special kind. It was made by logitech and the trackball was the size of a standard 8-ball or a bit smaller than a baseball. You basically rested most of your hand on the ball. It took a little bit to get used to but once I did, I couldn't live without it. Hell, even my mom liked it. It eliminated the pawing movement required when you play video games, and allowed lighting fast response and super accurate movements. Also the buttons were spread out enough that you could easily press any five of them with little or no thought, or delay. Too bad they don't make it anymore. As far as the small track balls go.... they suck.
Honestly if anyone knows where I can buy another one (my current one is showing signs of age), or buy something similar please tell me, price isn't really an issue, hell I'd even pay someone to custom build me another one.