The R9 290X and R9 290 do very well at multi monitor and 4K with multi GPU because of 2 factors
1.) better CF scaling
2.) better performance even as a single GPU at 4k and multi monitor because of the 512 bit memory bus and 64 ROPs
i am waiting for custom R9 290 cards to give the higher up cards a run for their money. you will see a lot of people pick two custom R9 290 cards for USD 850 - 900 instead of dropping USD 750 - 800 on a classy 780 ti or lightning 780 ti.