As much as I like all the space technology, I have to admit that I also think the money could be more wisely invested. I do think that it will eventually be a necessity for us to colonize space, but I see that need on at least a several centuries time scale, if not a couple millenia. I think we have much more pressing needs on the decades time scale right now that are not receiving the attention they need.
We have no magic bullet to the energy crisis right now, but I think there are some very promising options available. Nuclear fission seems to primarily be held back by waste disposal at the moment, but I noticed an interesting option on
wikipedia involving geological subduction zones that seems very promising if it can truly handle the quantities claimed. Fusion also seems very promising, but I think we need an intermediate solution given the expected timeframes for commercial deployment, which are still quite speculative at 30-50 years.
As for the cost of getting to the moon, I think everyone else pretty much covered it.
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Here's a helpful inflation calculator for determining todays dollars based on past inflation using actual historic inflation data. According to it,$25B in 1969 would be about $140B today. Of course that is looking only at inflation and not other increased costs (that would have to be separated from inflation).
-Also, safety regulations are much stricter than before. Our nation is not willing to tolerate the loss of even a handful of astronauts in a spectacular explosion, even though not nearly as much criticism is focused on US soldiers on foreign soil simply, in my opinion, because it is expected and less spectacular.
-We want to do more this time around than just land on the moon and bring back a few rocks. Developing a moon base will take a good bit more effort.
Of course, back to my original point, can you imagine what we could do on earth with $250B in funding?