Not necessarily. I'm sure there are some belief-based philosophies out there that adapt, albeit slowly, to new knowledge. Catholicism, as an example, eventually did accept that the sun doesn't orbit the earth, it just took them a couple hundred years to officially do so. Besides that, many of catholocism's followers adopted the heliocentric viewpoint long before their church did.
Besides that, as others have mentioned, organized belief systems aren't always the only ones opposed to new knowledge. Many of Darwin's critics, for example, were fellow scientists of his day. The main reason he waited so long to publish On the Origin of Species was because he hoped to release it posthumously, thereby evading backlash from the religious AND scientific communities.
Using myself as an example, I am highly religious in terms of believing in a God, but I adapt my beliefs and constantly question and assess my current understanding of them based on whatever new knowledge I acquire.