I run 2 monitors of different size and format (4:3 and 16:10), 19" 1280x1024 M-VA panel and 24" 1920x1200 S-IPS panel. I position the 24" directly in front of me with the 19" off to the left (panels touching) since I'm right-handed and my mouse/pad take up the right flank. I attempted to go 2x 24" panels with one being a TN panel but after turning it on I nearly drop-kicked it in disgust. Even with hours of settings adjustments I couldn't "fix" the washed-out look of everything on the panel. I learned my lesson. I was spoiled from using my IPS and VA panels and am stuck with them until they start mass-producing them again (hard to find these days for a decent price).